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Proc Natl Acad Sci U S A 99:1190813 Harvey CJ, Thimmulappa RK, Singh A, Blake DJ, Ling G, Wakabayashi N, Fujii J, Myers A, Biswal S (2009) Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

McIlvin M

3 showed that at visit 3, microbiota bacteria relative composition abundance levels were reduced for some taxa while enrichment was observed in other taxonomic families, but returned to similar baseline states in visit 4 and 5

Experts increasingly advocate aligning safety expectations for high-risk probiotic products (e.g., LBPs) with those applied to other complex biologicals, including systematic genomic characterization, standardized adverse-event reporting, and structured post-market surveillance, while avoiding unnecessarily stricter requirements than for comparable biologic therapies (525)